Unsubstituted Phenols
Apexbio Technology LLC L-690,330 142523-38-4 10mg
L-690 330 (CAS 142523-38-4) is a competitive inhibitor of inositol monophosphatase (IMPase) exhibiting a Ki between 0 2 and 2 M depending on the enzyme source IMPase catalyzes the hydrolysis of inositol monophosphates yielding free inositol for phosphatidylinositol (PI) cycle signaling In M1 CHO cells L-690 330 did not elevate [3H]InsP1 levels alone but attenuated carbachol-stimulated increases producing effects up to 40% of those observed with lithium In vivo L-690 330 administration led to significant Ins(1)P accumulation in mouse brain following muscarinic agonist stimulation These properties make L-690 330 a valuable tool for probing inositol signaling pathways and studying IMPase-related neurological processes
eMolecules Medchem Express / SKF 38393 (hydrochloride) / 50mg / 446261451 / HY-12520A / / 62717-42-4 / MFCD00069248 / 291.780 / C16H18ClNO2
Medchem Express / SKF 38393 (hydrochloride) / 50mg / 446261451 / HY-12520A / / 62717-42-4 / MFCD00069248 / 291.780 / C16H18ClNO2
Apexbio Technology LLC Edrophonium (chloride),250mg CAS# 116-38-1
Edrophonium is a competitive inhibitor of acetylcholinesterase (AChE) [1]. AChE is an extrinsic membrane-hound enzyme that functions in the central and peripheral nervous systems. AChE rapidly terminates the ACh receptor-mediated signal transmission by hydrolyzing Ach. Inhibition of AChE results in accumulation of ACh in the synaptic cleft and leads to impeded neurotransmission [2].In vitro: Edrophonium inhibited AChE activity in human red blood cells, purified calf forebrain, and octopus brain with Ki values of 0.2, 0.2, and 0.4 μM, respectively. The IC50s were 0.2, 0.05, and 0.5 μM, respectively [1]. Other sizes are also available. Please inqury us for quote.
eMolecules Medchem Express / Isosakuranetin / 5mg / 446275689 / HY-N2131 / / 480-43-3 / [null] / 286.283 / C16H14O5
Medchem Express / Isosakuranetin / 5mg / 446275689 / HY-N2131 / / 480-43-3 / [null] / 286.283 / C16H14O5
Medchemexpress LLC Tyrphostin AG1433 | 168835-90-3 | 99.1% | 5 MG
Tyrphostin AG1433 is a small-molecule tyrosine kinase inhibitor used in preclinical research to selectively inhibit PDGFRβ and VEGFR-2. It is supplied as a high-purity research chemical suitable for biochemical and cell-based assays, with documented solubility in DMSO and common in vivo vehicle formulations.
- High purity suitable for sensitive assays.
- Molecular weight 266.29 g/mol and formula C16H14N2O2.
- High DMSO solubility (~62.5 mg/mL) and in vivo vehicle solubility ≥ 2.08 mg/mL.
- Useful for probing PDGFR and VEGFR signaling in vitro and in vivo models.
- Typically stored as a powder at low temperature to preserve stability.
Enzo Life Sciences L-Thiocitrulline . dihydrochloride (50mg). CAS: 212051-53-1
Inhibitor of neuronal (nNOS; NOS I; Ki=60nM) and inducible (iNOS; NOS II) nitric oxide synthase. Formula: C6H13N3O2S . 2HCl. MW: 191.3 . 72.9. Purity: ≥97% (TLC). Appearance: White solid. Solubility: Soluble in water or DMSO. Long Term Storage: +4°C.
Enzo Life Sciences Tyrphostin 1 (20mg). CAS: 2826-26-8
An inactive tyrphostin, which may be used as a negative control. Purity: ≥99%. Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml). Long Term Storage: Ambient.
Medchemexpress LLC HY-N0377 5mg Medchemexpress, Liquiritigenin CAS:578-86-9 Purity:>98%
Medchemexpress, HY-N0377 5mg Liquiritigenin CAS:578-86-9 Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β ( ERβ ) agonist with an EC 50 of 36.5 nM for activation of the ERE tk-Luc. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.